paleo vs acne

Paleo Diet Vs Acne – Study Proves Paleo Diet Clears Acne


For years, people believed that Acne was all in the genetics. This is partly true but diet is now a major contributor as well. You will discover why in this article.

Paleo diet for beginners investigates the relationship between Paleo diet Vs Acne from a scientific point of view using a study (link is below in references section). This is a really long and through paper that is confusing so I have taken all the information and condensed it in this article.

Hopefully, this makes it easier to understand.

Paleo Diet Vs Acne

Acne is an epidemic that is strongly related to diet. Several studies have proved that the main food classes that promote acne are high glycemic load carbohydrates, milk and dairy products and saturated fats.

paleo vs acne

Insulin like growth factor 1 (IGF-1) is heavily implicated in the formation and development of acne. IGF-1 and insulin are balanced by the transcription factor fork head box 01 (Fox01) and vice versa.


Acne is a result of increased sebum production, insulin and growth factor IGF-1.


High levels of IGF-1 correlates with increased growth of sebaceous glands and associated increase in facial sebum excretion leading to acne.


So what is IGF-1

This plays a pivotal role in sebaceous lipid production. This hormone is responsible for signalling 4 other elements and that is an AR transcription factor (like a signal for lipid production), PPARy receptor (one that binds to the AR factor, a receptor in the liver (where all the magic happens) and a sterol binding protein (to transport lipids synthesis from liver to required locations.


This IGF-1 system is negatively regulated by levels of, Fox01 (This is the balance mechanism)


Fox01 reduces the amount of IGF-1 in the system to reduce lipid synthesis and the pathways that cause acne symptoms.


The amount of Fox01 is reduced by higher levels of the insulin in the system hence why scientists in this study have concluded that low carb diets or diets with low glycemic indexes lead to lower insulin levels and by default lower symptoms of acne as levels of IGF will be low and Fox01 will be higher.

paleo vs acne

In order to test this idea scientists observed a group of subjects on a “normal” western diet and another group of subjects on a Paleo diet for 4 weeks.


The subjects on the western diet exhibited higher levels of IGF-1, facial sebum and insulin leading to formation of acne on their skin.


The subjects on the Paleo diet had higher levels of Fox01, lesser sebum excretion and lower levels of insulin revealing much lower levels of acne on their skin.

Here’s A Video You May Find Interesting

Next steps

What are your thoughts on this? Would love to hear from you in the comments below?

This is a great reason why Paleo diet for beginners are proud to promote the benefits of leading a Paleo lifestyle

PS – Before you start on the Paleo Diet, take moment to check out my free eBook. It will save you a ton of time as I share the mistakes I made first time round and how to fix them.

Alfie Mueeth


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